Eric Dane, ‘Grey’s Anatomy’ and ‘Euphoria’ Star, Dies at 53

The TV star announced his diagnosis with ALS in 2025.

Eric Dane, the beloved TV star best known for his run playing Dr. Mark Sloan on “Grey’s Anatomy,” has died at the age of 53, his representatives announced in a statement. The news comes ten months after Dane publicly shared that he had been diagnosed with ALS.

“He spent his final days surrounded by dear friends, his devoted wife, and his two beautiful daughters, Billie and Georgia, who were the center of his world,” the statement reads. “Throughout his journey with ALS, Eric became a passionate advocate for awareness and research, determined to make a difference for others facing the same fight. He will be deeply missed, and lovingly remembered always. Eric adored his fans and is forever grateful for the outpouring of love and support he’s received. The family has asked for privacy as they navigate this impossible time.”

Born in San Francisco in 1972, Dane first emerged on television in the mid-1990s, but began to capture mainstream attention after playing the role of Jason Dean on “Charmed” for two seasons. In 2005, his career changed forever when he appeared as a guest star in Season 2 of “Grey’s Anatomy.” He became a series regular in Season 3, and his character, nicknamed “McSteamy,” remained a fixture of the show for six seasons. He departed the medical drama at the start of Season 9, but later returned for a dream sequence in a 2021 episode.

Dane continued to act steadily after “Grey’s Anatomy,” leading the TNT drama “The Last Ship” for five seasons and appearing in films such as “Burlesque” and “Bad Boys: Ride or Die.” He notably starred in “Euphoria” as Cal Jacobs, the troubled father of Jacob Elordi’s Nate Jacobs, and will be seen in the upcoming Season 3.

Dane is survived by his wife and two daughters. News of his death was first confirmed by People magazine.