Tam-Peli extends survival by nearly four months in relapsed small-cell lung cancer
The phase 3 TAISHAN-302 trial found that tambotatug pelitecan (Tam-Peli, YL201), a novel anti-B7-H3 antibody-drug conjugate, significantly improved overall survival, progression-free survival and objective ...
13 Sep 01:50 · Medical Xpress
Trial supports MRI surveillance over preventive brain radiation in small-cell lung cancer
Results from the international phase 3 SWOG S1827 MAVERICK trial show that brain MRI surveillance alone improved cognitive failure-free survival compared with MRI surveillance plus prophylactic cranial ...
13 Sep 01:50 · Medical Xpress
First-line trastuzumab deruxtecan significantly improves progression-free survival in HER2-mutant lung cancer
First-line treatment with trastuzumab deruxtecan (T-DXd) significantly improved progression-free survival compared with pembrolizumab plus platinum-based chemotherapy in patients with advanced or metastatic ...
14 Sep 01:50 · Medical Xpress
Zipalertinib plus chemotherapy significantly extends progression-free survival in first-line EGFR lung cancer
Adding zipalertinib to platinum-pemetrexed chemotherapy significantly improved progression-free survival in patients receiving first-line treatment for advanced non-small cell lung cancer (NSCLC) harboring ...
14 Sep 01:50 · Medical Xpress
Amivantamab-chemotherapy demonstrates longest overall survival reported for lung cancer with EGFR mutation
Results from the phase 3 PAPILLON study show that first-line amivantamab plus carboplatin-pemetrexed (amivantamab-chemotherapy) was associated with numerically longer overall survival compared with chemotherapy ...
14 Sep 01:50 · Medical Xpress
Combination therapy does not meet primary endpoints in first-line PD-L1-high metastatic non-small cell lung cancer
Sacituzumab govitecan (SG) plus pembrolizumab did not demonstrate a statistically significant improvement in progression-free survival compared with pembrolizumab alone as first-line treatment for patients ...
13 Sep 01:50 · Medical Xpress
last updated on 14 Sep 06:26