Scientists create gel that regrows tooth enamel

Scientists at the University of Nottingham have developed a gel that can regenerate tooth enamel, potentially solving a problem that has long plagued dentistry. Unlike existing fluoride treatments that merely slow decay, this protein-based gel mimics the natural proteins that build enamel during childhood, according to research published in Nature Communications.

The gel works by creating a scaffold that draws calcium and phosphate from saliva to form new mineral structures through a process known as "epitaxial mineralization." When applied to damaged teeth, it fills cracks and holes while promoting organized crystal growth that integrates seamlessly with existing healthy tissue. Testing showed the regenerated enamel performs just like natural enamel when subjected to brushing, chewing, and acidic foods.

"Dental enamel has a unique structure, which gives enamel its remarkable properties that protect our teeth throughout life," said Dr. Abshar Hasan, the study's lead author. The technology addresses a critical need, as enamel degradation affects nearly half the world's population and contributes to serious health complications, including diabetes and cardiovascular disease.

The researchers have launched startup company Mintech-Bio to commercialize the treatment, with hopes of releasing their first product next year.

Previously:
• Biotech startup developing drug to grow more teeth
• Silly pup is startled when he notices his teeth for the first time (video)
• Old dentists' office walls are full of thousands of 'buried teeth'