Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology.

Chimpanzee naive pluripotent stem cells (PSCs) can now be grown in cellular cultures, reveals a recent study. They successfully created chimpanzee early embryo models, called 'blastoids,' and found that the inhibition of a specific regulatory gene is essential for chimpanzee PSC self-renewal. They also developed a feeder-free culture system, eliminating the need for mouse-derived feeder cells as support. These findings provide valuable insights into primate embryology and could advance stem cell research and regenerative medicine.

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable tools ...